Mouse monoclonal antibody to non-erythrocyte alpha-spectrin [3D7]: Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

SPTAN1; alpha II spectrin; alpha Fodrin; Spectrin, non-erythroid alpha chain; SPTA2;

 

Antibody_Isotype
(Antibody only) : IgG1

 

Application_Details :

WB, ICC and IHC. Recommended dilution of 1:1,000-1:2,000 for ICC and IHC, and 1:5,000-10,000 for WB. The protein is seen as a major band at 240 kDa depending on the species. Optimal concentrations/dilutions should be determined by the end-user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : 3D7

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1178

 

Description (Long Description) : 

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. The Spectrins form into dimers and further into tetramers of alpha and beta subunits (Ref: Entrez Gene). The alpha-II subunit is widely expressed in tissues but, in the nervous system, is found predominantly in neurons.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized with 5% trehalose

 

Immunogen (Antigen) :This antibody was raised against a recombinant construct containing the seventh, eight and ninth repeats (amino acids 676-1043) of human alpha-II Spectrin. The 9th spectrin repeat also includes a Src-homology 3 domain. This construct was expressed in and purified from E. coli.

 

Kit_Components :

 

MSDS (File name) :