Mouse monoclonal antibody to Neurofilament Heavy [NF-200]: IgG

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

NF-200; NF200; NF-H; NEFH; N52; Neurofilament heavy polypeptide; Neurofilament triplet H protein; 200 kDa neurofilament protein; KIAA0845; NFH;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.50 µg/mL is recommended for WB. Human NF200 has a predicted length of 1026 residues and MW of 112 kDa. A concentration of 1.0-2.0 µg/mL is recommended to detect NF200 in formalin fixed and paraffin embedded tissues as well as formalin/acetone fixed tissues. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : NF-200

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=458

 

Description (Long Description) : 

Neurofilaments contain three intermediate filament proteins: light (68 kDa), medium (160 kDa) and heavy (200 kDa). Neurofilament heavy (NF200 or NF-H) is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. This antibody recognises both phosphorylated and dephosphorylated forms of NF200/NF-H.

 

Expiry_Date : 

12 months after purchase.

 

Format (Form) : 

Lyophilized from 1.2% sodium acetate, 2mg BSA, 0.01mg NaN3

 

Immunogen (Antigen) :C-terminal segment of enzymatically dephosphorylated pig Neurofilament Heavy (NF200).

 

Kit_Components :

 

MSDS (File name) :