Mouse monoclonal antibody to human Secretogranin-5 [8G11]: IgG
Antibodies
- 貨號 Cat. No.
- M-865-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human 、 Mouse 、 Rat
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Neuroendocrine protein 7B2; Secretory granule endocrine protein I; Secretogranin V; Pituitary polypeptide; SCG5; SGNE1
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 8G11
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=351
Description (Long Description) :
Secretogranin-5 is an acidic protein of 186 amino aids and has an expression that seems to be restricted to neurons and endocrine cells. In the brain, it is most abundant in the supraoptic and paraventricular nuclei of the hypothalamus. It acts in neuroendocrine cells as a specific chaperone for proprotein convertase-2 (PC2) which is an important endoprotease involved in the processing of neuroendocrine precursors. It binds to inactive proPC2 in the ER and facilitates its movement toward the secretory pathway where proPC2 is proteolytically matured and activated. It also plays a role in regulating pituitary hormone secretion.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant human Secretogranin-5 (amino acids 59-160) with a GST tag.
Kit_Components :
MSDS (File name) :
