Mouse monoclonal antibody to human Radical fringe homolog [6C7]: IgG
Antibodies
- 貨號 Cat. No.
- M-861-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Beta-1;3-N-acetylglucosaminyltransferase radical fringe; O-fucosylpeptide-3-beta-N-acetylglucosaminyltransferase; RFNG
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB, immunofluorescence and direct ELISA. The recommended dilution for this antibody is 10 µg/mL for immunofluorescence. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 6C7
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=347
Description (Long Description) :
The Drosophila melanogaster 'fringe' gene is a secreted signaling protein that is involved in the formation of boundaries between groups of cells during development. It acts by modulating the activation of te Notch signal transduction pathway. A human radical fringe homolog was identified in 1997. There is evidence to show that radical fringe homolog may be involve in limb formation and in neurogenesis in humans. It is a glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. It is a single-pass type II membrane protein which localises to the golgi apparatus membrane. It belongs to the glycosyltransferase 31 family.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant human Radical fringe homolog (amino acids 222-330) with a GST tag.
Kit_Components :
MSDS (File name) :
