Mouse monoclonal antibody to human NF-H [2E8]: IgG

Antibodies

貨號 Cat. No.
M-848-100
規格 Size
100 µg
品牌 Brand
Biosensis
Application 應用
ELISA 、 WB
Reactivity
Human
Host
Mouse
Clonality
Monoclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


Neurofilament heavy polypeptide; Neurofilament triplet H protein; 200 kDa neurofilament protein; NEFH; KIAA0845; NFH


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


This antibody is recommended for WB and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) : 2E8


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=334


 

Description (Long Description) : 


Neurofilaments contain three intermediate filament proteins: L, M and H, which are involved in the maintenance of the neuronal caliber. NF-H has an important function in mature axons. NF-H is phosphorylated and it is thought that this results in the formation of interfilament cross bridges that are important in the maintenance of axonal caliber. Defects in NF-H are a cause of amyotrophic lateral sclerosis (ALS) which is a neurodegenerative disorder affecting upper and lower motor neurons and results in fatal paralysis.


 

Expiry_Date : 


12 months after purchase

 

Format (Form) : 


Lyophilized from PBS pH 7.2

 

Immunogen (Antigen) :Partial recombinant human NF-H protein (263-364) with a GST tag.


 

Kit_Components :


 

MSDS (File name) :


 



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