Mouse monoclonal antibody to human LIMK-1 [1A8]: IgG
Antibodies
- 貨號 Cat. No.
- M-844-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
LIM domain kinase 1; LIMK1; LIMK
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB, IHC and sandwich ELISA. For IHC, a concentration of 3 µg/mL is recommended. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 1A8
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=400
Description (Long Description) :
LIMK-1 belongs to a small subfamily of LIM proteins with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 regulates actin filament dynamics. It phoshorylates and inactivates the actin binding/ depolymerising factor cofilin, consequently stabilising the actin cytoskeleton. It may also be involved in brain development. LIMK-1 localises to the cytoplasm and is highly expressed in both the adult and fetal nervous system. It is expressed to a lesser extent in heart and skeletal muscle. LIMK-1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant protein of human LIMK-1 (aa 548 to 648) with a GST tag.
Kit_Components :
MSDS (File name) :
