Mouse Monoclonal antibody to human JAG1 [1E12]

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Protein jagged-1; Jagged 1; hJ1; CD339 antigen; JAG1; JAGL1;

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

This antibody is recommended for direct ELISA and WB. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : 1E12

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=317

 

Description (Long Description) : 

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for multiple Notch receptors involved in the mediation of Notch signalling. It may be involved in cell-fate decision during hematopoiesis and seems to be involved in early and late stages of mammalian cardiovascular development. JAG1 is a trans membrane protein that is widely expressed in adult and fetal tissues. Mutations that alter the jagged 1 protein cause Alagille syndrome which is an autosomal dominant multisysstem disorder. Defects in JAG1 are also the cause of tetralogy of Fallot (TOF) which is a congenital heart anomaly.

 

Expiry_Date : 

12 months after purchase

 

Format (Form) : 

Lyophilized

 

Immunogen (Antigen) :Partial recombinant human JAG1 (amino acids 531-621) with a GST tag

 

Kit_Components :

 

MSDS (File name) :