Mouse monoclonal antibody to human dynactin subunit 1 [1E12]: IgG
Antibodies
- 貨號 Cat. No.
- M-822-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
150 kDa dynein-associated polypeptide; DP-150; DAP-150; p150-glued; p135; DCTN1
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB and direct ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 1E12
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=304
Description (Long Description) :
Dynactin subunit 1 (DCTN1) is part of a large macromolecular complex of at least 10 components. It is required for cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. Dynactin subunit 1 binds directly to microtubules and to cytoplasmic dynein. It is expressed in the brain and localises to the cytoplasm and the cytoskeleton. It belongs to the dynactin 150 kDa subunit family and contains one CAP-Gly domain. Abnormalities in DCTN1 cause progressive lower motor neuron disease (PLMND).
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial sequence recombinant protein of human dynactin subunit 1 (amino acids 1082-1270) with GST tag
Kit_Components :
MSDS (File name) :
