Mouse monoclonal antibody to human cytochrome P450 46A1 [1A11]: IgG
Antibodies
- 貨號 Cat. No.
- M-821-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Cholesterol 24-hydroxylase; CH24H; CYP46A1; CYP46
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB and direct and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 1A11
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=303
Description (Long Description) :
Cytochrome P450 46A1 belongs to the cytochrome P450 family which are a group of monooxygenases. Cytochrome P450 46A1 is involved in the turnover of cholesterol converting it into 24S-hydroxycholesterol and, to a lesser extent, 25-hydroxycholesterol. This protein is expressed in the brain and mRNA has been found to be broadly distributed with higher levels in the gray matter zones and lower levels in white matter areas. It is not detected in fetal brain but its expression increases linearly with age. It localises to the endoplasmic reticulum membrane and the microsome membrane. The unprocessed precursor is 500 amino acids long and has a predicted molecular weight of 56.8KDa.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant protein of human cytochrome P450 46A1 (amino acids 201 to 300) with a GST tag.
Kit_Components :
MSDS (File name) :
