Mouse monoclonal antibody to human CRIM1 [6E4]: IgG

Antibodies

貨號 Cat. No.
M-817-100
規格 Size
100 µg
品牌 Brand
Biosensis
Application 應用
ELISA 、 IHC, Frozen 、 WB
Reactivity
Human
Host
Mouse
Clonality
Monoclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


Cysteine-rich motor neuron 1 protein; cysteine-rich repeat-containing protein S52; CRIM1


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


This antibody is recommended for IHC at a dilution of 3 µg/mL. It is also recommended for sandwich ELISA with a detection limit for the recombinant GST tagged CRIM1 protein of 0.03 ng/mL. This antibody is useful for WB analysis. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) : 6E4


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=296


 

Description (Long Description) : 


CRIM1 may participate in CNS development by interacting with growth factors involved in motor neuron differentiation and survival. It also has a potential role in capillary formation and maintenance during angiogenesis. It also affects BMP processing and delivery to the cell surface. CRIM1 interacts with BMP4 and BMP7. It localises to the cell membrane and is expressed in a number of tissues including the pancreas, kidney, skeletal muscle, lung, placenta, brain, heart, spleen, liver, small intestine and blood vessels. The unprocessed precursor has a length of 1036 amino acids and a predicted molecular weight of 113.7KDa. CRIM1 contains four antistatin-like domains, one IGFBP N-terminal domain and six VWFC domains. It is also N-glycosylated.


 

Expiry_Date : 


12 months after purchase

 

Format (Form) : 


Lyophilized from PBS pH 7.2

 

Immunogen (Antigen) :A partial recombinant human CRIM1 protein (amino acids 36 to 145) with a GST tag.


 

Kit_Components :


 

MSDS (File name) :


 



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