Mouse monoclonal antibody to human CD97 antigen [5D5]: IgG
Antibodies
- 貨號 Cat. No.
- M-811-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Leukocyte antigen CD97
Antibody_Isotype
(Antibody only) :
Application_Details :
WB, direct and sandwich ELISA are recommended for this antibody. In sandwich ELISA this antibody has a detection limit of 0.1 ng/mL for recombinant GST tagged CD97 antigen. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 5D5
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=288
Description (Long Description) :
CD97 antigen is a receptor involved in both adhesion and signaling processes early after leukocyte activation. It also plays an essential role in leukocyte migration. The unprocessed precursor is 853 amino acids long and has a predicted molecular weight of 91.9KDa. CD97 antigen is a heterodimer consisting of a large extracellular alpha subunit and a seven-transmembrane beta subunit that are non-covalently linked. It contains five EGF-like domains and one GPS domain. This protein interacts with complement decay-accelerating factor (DAF) through the first two EGF domains, and with chondroitin sulfate (only isoform 1) through the fourth EGF domain. CD97 antigen is broadly expressed and it is present on most hematopoietic cells. It is also abundantly expressed by smooth muscle cells. Expression of this protein is increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients of rheumatoid arthritis. This protein is rapidly up-regulated during lymphocyte activation. C97 antigen belongs to the G-protein coupled receptor 2 fmaily and the LN-TM7 subfamily.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant protein of human CD97 antigen (amino acids 421 to 529) with a GST tag.
Kit_Components :
MSDS (File name) :
