Mouse monoclonal antibody to human CaM kinase 1 [3G1]: IgG
Antibodies
- 貨號 Cat. No.
- M-810-100
- 規格 Size
- 100 µg
- 品牌 Brand
- Biosensis
- Application 應用
- ELISA 、 WB
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Calcium/calmodulin-dependent protein kinase type 1; CaM-KI; CaM kinase I alpha; CAMKI-alpha; CAMK1
Antibody_Isotype
(Antibody only) :
Application_Details :
This antibody is recommended for WB and both direct and sandwich ELISA. This antibody has a detection limit of 0.3ng/mL for recombinant GST tagged CaM kinase 1 when used in sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) : 3G1
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=285
Description (Long Description) :
CaM kinase I belongs to a calcium-triggered signalling cascade involved in trasncriptional regulation, hormone production, translational regulation, regulation of actin filament organisation and neurite outgrowth. CaM kinase I is involved in calcium-dependent activation of the ERK pathway. It phosphorylates proteins with the substrate consensus sequence [MVLIF}-x-R-x(2)-[ST]-x(3)-[MVLIF]. It is activated by calcium ions or calmodulin. It reaches its maximum catalytic activity when phosphorylated by CAMKK1 or CAMKK2. CaM kinase I has a length of 370 amino acids (unprocessed precursor) and a predicted molecular weight of 41.3KDa. It is a monomer that exists in many tissues and is located within the cytoplasm or nucleus. It belongs to the protein kinase superfamily, the CAMK Ser/Thr protein kinase family and the CaMK subfamily.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized from PBS pH 7.2
Immunogen (Antigen) :Partial recombinant protein of human CaM kinase 1 (amino acids 271 to 370) with a GST tag.
Kit_Components :
MSDS (File name) :
