Mouse monoclonal antibody to human CAB2 [6C1]: IgG

Antibodies

貨號 Cat. No.
M-809-100
規格 Size
100 µg
品牌 Brand
Biosensis
Application 應用
ELISA 、 WB
Reactivity
Human 、 Mouse 、 Rat
Host
Mouse
Clonality
Monoclonal

Description




ZZZZ_Status (Active, Disc) : Active


 

AA_Supplier Name : Biosensis


 

Alternative_Name (Other Names) :


Voltage-dependent L-type calcium channel subunit beta-2; calcium channel voltage-dependent subunit beta 2; Lambert-Eaton myasthenic syndrome antigen B; MYSB; CACNB2


 

Antibody_Isotype
(Antibody only) :


 

Application_Details :


This antibody is recommended for WB, direct and sandwich ELISA. The detection limit for recombinant CAB2 protein with GST tag is 0.1ng/mL when this antibody is used in sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.


 

Background_Info :


 

Clone_Name
(AB only, monoclonals) : 6C1


 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=284


 

Description (Long Description) : 


The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma. The beta subunit of voltage-dependent calcium channels aids the function of the calcium channel by increasing the peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. CAB2 is a membrane protein that is expressed in all tissues. The unprocessed precursor is 660 amino acids in length and has a predicted molecular weight of 74.5KDa. It belongs to the calcium channel beta subunit family and contains one SH3 domain. CAB2 is involved in the MAPK signalling pathway and is also associated with Lambert-Eaton myasthenic syndrome.


 

Expiry_Date : 


12 months after purchase

 

Format (Form) : 


Lyophilized from PBS pH 7.2

 

Immunogen (Antigen) :This antibody was raised against a partial recombinant protein of human CAB2 (amino acids 213 to 301) with a GST tag.


 

Kit_Components :


 

MSDS (File name) :


 



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