Mouse monoclonal antibody to human AHNAK nucleoprotein [3G7]: IgG

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Desmoyokin; AHNAK

 

Antibody_Isotype
(Antibody only) :

 

Application_Details :

This antibody is recommended for use in WB , direct ELISA and sandwich ELISA. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : 3G7

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=276

 

Description (Long Description) : 

Neuroblast differentiation-associated protein or AHNAK and known as desmoyokin, is a large protein (molecular mass, 700 kD) phosphoprotein that can be found as a nuclear protein, a structural scaffold protein and a plasma membrane protein. It was originally identified first as a nuclear phosphoprotein, then later as scaffold protein bovine and named desmoyokin due to its localization pattern in the desmosomal plaque. AHNAK has been shown to be essential for pseudopod protrusion and cell migration but may also play key roles in blood-brain barrier formation, cell structure and migration, cardiac calcium channel regulation, and tumor metastasis.

 

Expiry_Date : 

12 months upon purchase.

 

Format (Form) : 

Lyophilized from PBS pH 7.2, 150mM NaCl.

 

Immunogen (Antigen) :Partial recombinant human AHNAK protein (1-101) with a GST tag. It is reported that the monoclonal epitope is the N-terminal part of AHNAK1.

 

Kit_Components :

 

MSDS (File name) :