Mouse IL1R1 / CD121a Protein (His Tag)

Species : Mouse

Synonyms : CD121a,CD121b,IL-1R1,IL-iR,Il1r-1

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE

Activity : 1. Measured by its ability to bind mouse IL1B in a functional ELISA. Immobilized mouse IL1A at 10 £gg/mL (100 £gl/well) can bind mouse IL1R1, The EC50 of mouse IL1R1 is 0.13 £gg/mL.
2. Measured by its ability to inhibit Interferon gamma secretion by human natural killer lymphoma NK-92 cells in the presence of 20 ng/mL rmIL1£. The EC50 for this effect is typically 20-80 ng/mL.