Mouse Glycophorin A / CD235a Protein, Fc,His Tag

Source : 

Mouse Glycophorin A, Fc,His Tag (CDA-M526x) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Val 108 (Accession # P14220).

 

Molecule : Glycophorin A

 

Synonyms : CD235a,Glycophorin-A,Gypa

 

Format : Powder

 

Category : Bio-Markers & CD Antigens

 

Accession : N/A

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 39.1 kDa

 

Characteristics :

This protein carries a human IgG1 Fc tag at the N-terminus and a polyhistidine tag at the C-terminus. The protein has a calculated MW of 39.1 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : Tris with Glycine, Arginine and NaCl, pH7.5

 

Description :

Glycophorin-A, a member of the glycophorin-A family, is also known as CD235a and Gypa, which is heavily glycosylated on serine and threonine residues at the N-terminal extracellular domain. CD235a,a single-pass type III membrane protein,is the major intrinsic membrane sialoglycoprotein of the erythrocyte. Also,CD235a appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. Furthermore,CD235a may be involved in translocation of SLC4A1 to the plasma membrane.

 

References :

(1) Arimitsu N., et al., 2003, Genes Cells 8:769-777.