Mouse DLL4 / Delta4 Protein (His Tag)

Species : Mouse

Synonyms : Delta4

Host : HEK293 Cells

Purity :> 96 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA. Immobilized mouse DLL4-his (Cat:50640-M08H) at 10 £gg/mL (100 £gL/well) can bind biotinylated mouse NOTCH1-his. The EC50 of biotinylated mouse NOTCH1-his is 30 ng/mL.
2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 1-5 ?g/mL in the presence of 500 ng/mL recombinant human BMP2.