Mouse CTLA4 / CD152 Protein (ECD,His Tag)

Species : Mouse

Synonyms : Cd152,Ctla-4,Ly-56

Host : HEK293 Cells

Purity :> 95 % as determined by SDS-PAGE

Activity : 1. Measured by its binding ability in a functional ELISA.
2. Immobilized recombinant mouse CTLA4-His (Cat:50503-M08H) at 10 £gg/ml (100 £gl/well) can mouse CD80-Fc (cat:50446-M02H) with a linear range of 0.78-62.5 ng/ml.
3. Immobilized recombinant mouse CTLA4-His (Cat:50503-M08H) at 10 £gg/ml (100 £gl/well) can human B7-1-Fc (Cat:10698-H03H) with a linear range of 0.78-125 ng/ml.
4. Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.1-0.5£gg/mL when stimulated with 1 £gg/mL Recombinant Human B7-1/CD80.