Mouse antibody to human methyl-CpG binding protein 2 (MeCP2) [4F11]: Affinity purified

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

MeCP2, MeCp-2 protein

 

Antibody_Isotype
(Antibody only) : IgG1

 

Application_Details :

Western blotting (1:5,000-1:10,000) and Immunohistochemistry (1:1,000-1:5,000). Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) : 4F11

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1631

 

Description (Long Description) : 

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). Ref: uniprot.org

 

Expiry_Date : 

12 months after purchase if unopened.

 

Format (Form) : 

Lyophilized from a solution containing PBS buffer pH 7.2-7.6 with 3% trehalose, without preservatives.

 

Immunogen (Antigen) :Full-length recombinant human protein

 

Kit_Components :

 

MSDS (File name) :