Monensin Antibody

Monensin A (Monensin) is a polyether ionophore antibiotics isolated from Streptomyces cinnamonensis, and is perhaps the most representative drug of this group. Monensin is able to transport cations, specifically Li+, Na+, K+, Rb+, Ag+ and Tl, across lipid membranes of cells, playing an important role as a Na+/H+ antiporter. Monesin blocks intracellular protein transport, and exhibits antibiotic, antimalarial, and other biological activities. The antibacterial properties of monensin and its derivatives are attributable to their ability to transport metal cations through cellular and subcellular membranes.