MMP-2 Polyclonal Ab

貨號 Cat. No.
3522-100
規格 Size
100 ug

Description

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pbHOST:/b Rabbit/p
pbFORMULATION:/b 100 ug (0.2 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide./p
pbSPECIES REACTIVITY:/b human, mouse, rat/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND:/b The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV, V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway./p
pbSPECIFICITY:/b The antibody recognizes MMP-2 of human, mouse, and rat origins. A 72 kDa band can be detected./p
pbAPPLICATION:/b The antibody can be used in Western blotting (1-4 ug/ml), immunoprecipitation (10-20 ug/ml), and immunohistochemistry (15-25 ug/ml). However, the optimal concentrations should be determined individually./p
pbUSAGE:/b For Research Use Only. Not to be used in human./p

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