MMP-12 Polyclonal Ab
- 貨號 Cat. No.
- 3532-100
- 規格 Size
- 100 ug
Description
pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= /nbsp;/p
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pbHOST:/b Goat FORMULATION: 100 ?g (0.2 mg/ml) purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide./p
pbSPECIES REACTIVITY: /bhuman STORAGE CONDITIONS: Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles. BACKGROUND: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders./p
pbSPECIFICITY: /bThe antibody recognizes the MMP-12 of human origin. Reactivity to other species has not been tested./p
pbAPPLICATION: /bThe antibody can be used in Western blotting (1-4 ?g/ml). However, the optimal concentrations should be determined individually. USAGE:/p
pbFor Research Use Only. Not to be used in human. /b/p
pfont size=2 /font/p
pbHOST:/b Goat FORMULATION: 100 ?g (0.2 mg/ml) purified goat polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% sodium azide./p
pbSPECIES REACTIVITY: /bhuman STORAGE CONDITIONS: Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles. BACKGROUND: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders./p
pbSPECIFICITY: /bThe antibody recognizes the MMP-12 of human origin. Reactivity to other species has not been tested./p
pbAPPLICATION: /bThe antibody can be used in Western blotting (1-4 ?g/ml). However, the optimal concentrations should be determined individually. USAGE:/p
pbFor Research Use Only. Not to be used in human. /b/p