MLN8054
Chemical Compounds
- 貨號 Cat. No.
- M1751
- 規格 Size
- 10mg,50mg,100mg
- 品牌 Brand
- No Brand
Description
MLN8054 is an orally bioavailable, highly selective small molecule inhibitor of Aurora with IC50s of 0.004uM and 0.172uM. for Aurora A and Aurora B.Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregration, and inhibition of cell proliferation.
