MLH1 Peptide

h1 class=titleMLH1 Peptide/h1
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h4Catalog Number/h4
pstrong350529/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Price/h4
pstrong$50.00/strong/p
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h4Description/h4
pDNA mismatch repair protein Mlh1 (MLH1) is involved in the repair of DNA mismatches. MLH1 is part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBS1 protein complex. Defects in MLH1 are the cause of hereditary non-polyposis colorectal cancer type 2, Turcot syndrome, Muir-Torre syndrome, including brain, colorectal, breast and endometrial tumors./p
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h4Format/h4
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pEach vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect./p
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h4Product Citations/h4
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h4Recommended Products/h4
pa href=http://abbiotec.com/antibodies/mlh1-antibody200167 MLH1 Antibody/abr /
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h4Alternate Names/h4
pDNA mismatch repair protein Mlh1; MutL protein homolog 1; MLH1; COCA2/p
h4Accession No./h4
pa class=accession-link href=http://www.expasy.org/uniprot/P40692 target=_blankP40692/abr /
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h4MW/h4
p1851 g/mol/p
h4Sequence/h4
pThe synthetic peptide used to raise the antibody Cat. No. 200167 is selected from a sequence within the C-term region of human MLH1. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended./p
h4Composition/h4
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pC80H123N25O24S1/p
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h4Purity/h4
pPurity gt; 80% by HPLC/p
h4Solubility/h4
pDistilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile./p
h4Storage/h4
pStore at -20deg;C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20deg;C./p
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