MI-2
Chemical Compounds
- 貨號 Cat. No.
- M3639
- 品牌 Brand
- No Brand
Description
MI-2 binds directly to MALT1 and irreversibly suppresses protease function. MI-2 decreases NF-κB activity induced by MALT1. MI-2 inhibits cell proliferation and MALT1-mediated cleavage activity. MI-2 concentrates within human ABC-DLBCL cells and irreversibly inhibited cleavage of MALT1 substrates. MI-2 displayes selective activity against ABC-DLBCL cell lines in vitro and xenotransplanted ABC-DLBCL tumors in vivo.
