MGMT Antibody

Antibodies

貨號 Cat. No.: 251378
規格 Size: 0.1 mg
品牌 Brand: Abbiotec
Application 應用: ELISA 、 WB
Reactivity: Human 、 Mouse

Description

Methylated-DNA--protein-cysteine methyltransferase (MGMT) is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

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