MDC Polyclonal Ab

貨號 Cat. No.
5454-100
規格 Size
100 ug

Description

pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= /nbsp;/p
pfont size=2 /font/p
pbIMMUNOGEN:/b E. coli-expressed human MDC/p
pbHOST:/b Rabbit/p
pbFORMULATION:/b 100 ug (0.5 mg/ml) purified rabbit anti-human MDC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide./p
pbSPECIES REACTIVITY:/b human/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long-term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND DESCRIPTION:/b MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a N-terminal sequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages. Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells. MDC has anti-HIV-1 activity. Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1? and TNF?. MDC is a functional ligand for CCR4./p
pbAPPLICATION:/b The antibody can be used for Western blot analysis (0.5-1 u?/ml) and ELISA (2-3 ug/ml). However, the optimal conditions should be determined individually./p
p1. Godiska, R., et al. (1997) J. Exp. Med. 185:1595-1604. 2. Pal, R., et al. (1997) Science 278:695-698./p
pnbsp;/p
pbREFERENCES: /b:/p
pbFOR RESEARCH PURPOSE ONLY! Not to be used in human subjects! /b/p
pnbsp;/p

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