Mannan-binding Lectin Horse (15C5) Antibody

h1 class=titleMannan-binding Lectin Horse (15C5) Antibody/h1
div id=node-556 class=node ntype-antibodiesMouse Monoclonal
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h4Catalog Number/h4
pstrong250356/strong/p
h4Unit/h4
pstrong0.2 mg /strong/p
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Format/h4
pEach vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography./p
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h4Description/h4
pMannan-binding lectin (MBL), also called mannose-binding lectin or protein, belongs to the C-type family of collectins, showing calcium-dependent binding to certain sugars. It consists of oligomers of triple-chain subunits and its binding and complement activating activities depend on its normal oligomerization. On binding to mannan-like microbial surface carbohydrates, MBL activates the complement system by means of its own lectin pathway, depending on the MBL-associated serine proteases (MASPs). Because of the presence of different structural and promoter alleles in the population, 12% or more of the population have low concentrations (lt;50ng/mL) of normally oligomerized, functional MBL in plasma or serum. This antibody is specific for human MBL from plasma or serum, but cross-reacts strongly with MBL from horse and swine./p
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h4Product Citations/h4
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h4Recommended Products/h4
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h4Alternate Names/h4
pMannose-binding protein C;nbsp; MBP-C;nbsp; MBP1;nbsp; Mannose-binding lectin; mannan-binding protein; MBL2; MBL/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P11226P11226/abr /
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h4Clonality/h4
p15C5/p
h4Antigen/h4
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pMBL purified from human donor plasma and adsorbed onto aluminum hydroxide/p
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h4Application Notes/h4
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pProduct Cat. No. 250356 reacts strongly with human, horse and swine serum in ELISA when immobilized on mannan-coated microplate. A weaker reaction is seen when Product Cat. No. 250356 is used as a detection antibody for human MBL coated directly onto the microtiter plate./p
pE: 1:250/p
pWB: 1:100/p
pstrongReacts with/strongnbsp; :H | Other/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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