LY2228820
Chemical Compounds
- 貨號 Cat. No.
- M2318
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
LY2228820 is a novel and potent p38MAPK inhibitor. In vitro kinase enzyme activity showed that the IC50 for p38αMAPK and p38βMAPK of LY2228820 were 7 nM and 3 nM, respectively. Phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, was significantly inhibited by LY in both MM cell lines and LT-BMSCs.
