LTF / Lactoferrin Antibody (LS-B2636)

貨號 Cat. No.: LS-B2636
規格 Size: 50 Âµg
品牌 Brand: LSBio

Description

Antibody Catalog ID:	LS-B2636
Antibody Validation:	This antibody replaces catalog number LS-C58300. It has been validated for use in the following assays: IHC-P.
Antibody Target:	LTF / Lactoferrin
Synonyms:	LTF, GIG12, HLF2, lactotransferrin, LF
Host:	LTF antibody was produced in Mouse
Antigen Species:	LTF antibody was raised against Human
Clonality:	Monoclonal
Isotype:	IgG1
Antibody Clone Name:	1A1
Antigen Type:	Purified protein
Immunogen:	LTF antibody was raised against purified lactoferrin from human milk
Antibody Specificity:	Recognizes human lactoferrin, a 78kD globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals. Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses. May be used to detect lactoferrin in ELISA assays.
Purification:	Affinity Chromatography
Presentation:	PBS, pH 7.4, 0.09% sodium azide.
Recommended Storage:	+4°C or -20°C, Avoid repeated freezing and thawing.
Antibody Usage Summary:	Immunohistochemistry: LS-B2636 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2636 was determined to be 10 ug/ml. ELISA: May be used in an indirect ELISA or as a detection antibody in a sandwich ELISA together with LS-C58299 as a capture agent.
Antibody Uses:	Immunohistochemistry - Paraffin (IHC-P) (10 µg/ml), Western blot (WB), ELISA (Optimal dilution to be determined by the researcher)
Size:	50 µg
Concentration:	1 mg/ml