Lipocalin-2/NGAL (Mouse) ELISA Kit

Alternate Name :

Tag Line :

A Sandwich ELISA kit for the quantitative measurement of Lipocalin-2 in mouse serum, plasma, culture supernatants and other biological fluids.

Storage Conditions: 4°C

Shelf life: 12 months

Summary :

• Detection method- Absorbance (450 nm)
• Species reactivity- Mouse
• Application- quantitative measurement of Lipocalin-2 in mouse serum, plasma, tissue homogenates and other biological fluids.

Detection Method: Absorbance (450 nm)

Features & Benefits:

Easy, convenient and time-saving method to measure the level of Lipocalin-2 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids.
Detection Range: 78.125 - 5000 pg/ml
Sensitivity: < 46.875 pg/ml
Assay Precision: Intra-Assay: CV < 8%; Inter-Assay: CV < 10%
No significant cross-reactivity or interference was observed.

Description:

NGAL is involved in innate immunity by sequestrating iron that in turn limits bacterial growth. It is expressed in neutrophils and in low levels in the kidney, prostate, and epithelia of the respiratory and alimentary tracts. NGAL is used as a biomarker of kidney injury. Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. BioVision’s Lipocalin-2 ELISA kit is a sandwich ELISA assay for the quantitative measurement of Lipocalin-2 in mouse serum, plasma and cell culture supernatants. The density of color is proportional to the amount of Lipocalin-2 captured from the samples.