Linifanib (ABT-869)
- 貨號 Cat. No.
- A10025-5
- 規格 Size
- 5mg
- 品牌 Brand
- AdooQ
Description
Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively.
In vitro (25°C) | DMSO | 75 mg/mL (199.78 mM) |
Water | <1 mg/mL (<1 mM) | |
Ethanol | <1 mg/mL (<1 mM) | |
In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
0.1 mM | 26.64 mL | 133.19 mL | 266.38 mL |
0.5 mM | 5.33 mL | 26.64 mL | 53.28 mL |
1 mM | 2.66 mL | 13.32 mL | 26.64 mL |
5 mM | 0.53 mL | 2.66 mL | 5.33 mL |
*The above data is based on the productmolecular weight 375.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
CATALOG NUM | A10025 |
ACTIONS | Inhibitor |
M. WT | 375.4 |
FORMULA | C21H18FN5O |
SOLUBILITY | DMSO |
PURITY | >98% |
STORAGE | at -20°C 3 years Powder |
CAS NO. | 796967-16-3 |
SYNONYMS | ABT869, ABT-869 |
SMILES | CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N |