LINGO1 Antibody
Antibodies
- 貨號 Cat. No.
- 251546
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC 、 IP
- Reactivity
- Chicken 、 Human 、 Mouse
Description
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (LINGO1) is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also a negative regulator of oligodentrocyte differentiation and axonal myelination. LINGO1 acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development.
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