LAQ824
Chemical Compounds
- 貨號 Cat. No.
- M1747
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
LAQ824 (NVP-LAQ824) is a potent novel histone deacetylase (HDAC) inhibitor with an IC50 of 0.032 μM. NVP-LAQ824 also inhibited patient MM cell growth in a dose- and time-dependent manner. NVP-LAQ824-induced apoptotic signaling includes up-regulation of p21, caspase cascade activation, and poly (adenosine diphosphate [ADP]) ribose (PARP) cleavage.
