Lapatinib Ditosylate
- 貨號 Cat. No.
- 1624-25
- 規格 Size
- 25 mg
Description
Alternate Name/Synonyms: GW-57201, Tykerb, Tyverb
Appearance: Yellow solid
Formulation: N/A
CAS Number: 957054-30-7
Molecular Formula: C₂₉H₂₆ClFN₄O₄S.2C₇H₈O₃S
Molecular Weight: 925.46
Purity: ≥99% by HPLC
Solubility: DMSO (200 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: RT
Description: Lapatinib is a potent inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM), ErbB-4 kinase (Ki = 347 nM). Lapatinib can restore tamoxifen sensitivity in tamoxifen-resistant, ER-positive breast cancer models.
Handling: Protect from air and moisture