Labetalol hydrochloride

Labetalol hydrochloride is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors. Labetalol induces impaired cerebral autoregulation (CA) during the first day of life, with CA returning to a normal status by the third day after birth. This effect was hypothesized to be caused by labetalol-induced vasodilation. Labetalol HCl is used in the treatment of hypertensive disorders of pregnancy (HDP).