Kits
Kynurenine (IDK® Kynurenine) (dried blood samples) ELISA
Kits
Description
L-kynurenine is the main product of the degradation of L-tryptophan, catalyzed by
Indoleamine 2,3-dioxygenase (IDO).
L-kynurenine plays a key role as an immune suppressor in the course of infectious
diseases (HIV [1], tuberculosis [14], borreliosis [10] etc.) and malignant diseases (colon
cancer [2], lung cancer [5, 4], leukemia [8], Hodgkin lymphoma [3], cervical cancer
[7]), where high kynurenine levels indicate a poor prognosis. Thus, L-kynurenine
serves as a prognostic marker to predict the progression and the severity of the disease.
Indoleamine 2,3-dioxygenase (IDO).
L-kynurenine plays a key role as an immune suppressor in the course of infectious
diseases (HIV [1], tuberculosis [14], borreliosis [10] etc.) and malignant diseases (colon
cancer [2], lung cancer [5, 4], leukemia [8], Hodgkin lymphoma [3], cervical cancer
[7]), where high kynurenine levels indicate a poor prognosis. Thus, L-kynurenine
serves as a prognostic marker to predict the progression and the severity of the disease.