Proteins and Peptides
KMO Antibody (aa300‑400)
Antibodies
- 貨號 Cat. No.
- LS-C209356-100
- 規格 Size
- 100 µg (1.08 mg/ml)
- 品牌 Brand
- LSBio
- Application 應用
- ELISA 、 IHC
- Reactivity
- Human 、 Mouse
- Conjugate
- Unconjugated
Description
KMO antibody LS-C209356 is an unconjugated rabbit polyclonal antibody to KMO from human and mouse. Validated for ELISA, IF, IHC and WB.
About KMO
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Uniprot: O15229 NCBI: NM_003679 NP_003670.2
About KMO
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Uniprot: O15229 NCBI: NM_003679 NP_003670.2


