KMO Antibody (aa300‑400)

Antibodies

貨號 Cat. No.
LS-C209356-100
規格 Size
100 µg (1.08 mg/ml)
品牌 Brand
LSBio
Application 應用
ELISA 、 IHC
Reactivity
Human 、 Mouse
Conjugate
Unconjugated

Description

KMO antibody LS-C209356 is an unconjugated rabbit polyclonal antibody to KMO from human and mouse. Validated for ELISA, IF, IHC and WB.
About KMO
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. Uniprot: O15229 NCBI: NM_003679 NP_003670.2

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