Kallikrein-14 Antibody

Kallikrein-14 is a serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. Kallikrein-14 can both activate and inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. Kallikrein-14 functions in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3.