JNK-IN-8
Chemical Compounds
- 貨號 Cat. No.
- M2013
- 規格 Size
- 10mg,50mg
- 品牌 Brand
- No Brand
Description
JNK-IN-8 is a highly selective JNK inhibitor based on multiple profiling strategies. JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively. JNK-IN-8 inhibits c-Jun phosphorylation at submicromolar concentrations in cells. JNK-IN-8 will be broadly useful as a pharmacological probe of JNK-dependent signal transduction.
