ISG15
- 貨號 Cat. No.
- UL-601
- 規格 Size
- 500 μg
- 品牌 Brand
- Boston Biochem
Description
ISG15
human recombinant
Product Information
500 μg
X mg/ml (X μM) in 50 mM HEPES pH 8.0, 100 mM NaCl. Actual protein concentration will vary with specific Lot #.
17 kDa
> 95% by SDS-PAGE
Use & Storage
Store at -80°C. Avoid multiple freeze/thaw cycles.
Catalog #: UL-601
ISG15
Product Source:
human recombinant
Also known as: UCRP
The ubiquitin-like ISG15 is conjugated to intracellular target proteins. This pathway is distinct from that of ubiquitination with different in substrate specificity and interaction with ligating enzymes. ISG15 becomes conjugated to a diverse set of proteins after IFN-α/β stimulation or microbial challenge. The functions or biochemical consequences ISG15 conjugation to proteins are not yet known, but it appears that this modification does not target proteins for proteasomal degradation. ISG15 shows specific chemotactic activity towards neutrophils and activates them to induce release of eosinophil chemotactic factors. It may also serve as a trans-acting binding factor directing the association of ligated target proteins to intermediate filaments and may also be involved in autocrine, paracrine and endocrine mechanisms.
Product Information
Quantity:
500 μg
Stock:
X mg/ml (X μM) in 50 mM HEPES pH 8.0, 100 mM NaCl. Actual protein concentration will vary with specific Lot #.
MW:
17 kDa
Purity:
> 95% by SDS-PAGE
Use & Storage
Storage:
Store at -80°C. Avoid multiple freeze/thaw cycles.