IRS-2 Antibody

h1 class=titleIRS-2 Antibody/h1
div id=node-1560 class=node ntype-antibodiesRabbit Polyclonal
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h4Catalog Number/h4
pstrong250727/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
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Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe family of insulin receptors substrates (IRSs) has been reported to play an important role for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insukin receptor substrate 2, a cytoplasminc signaling molecule that mediates effects of insulin , insulin like growth factor 1 and other cytoines by acting as a molecular adaptor betwenn diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interlukin 4 receptor-associated kinase in response to IL4 treatment./p
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h4Product Citations/h4
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h4Alternate Names/h4
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h4Accession No./h4
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h4Clonality/h4
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h4Antigen/h4
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pKLH-conjugated synthetic peptide encompassing a sequence within the N/C-term region of human protein./p
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h4Application Notes/h4
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pE: 1:500-1:1,000/p
pWB: 1:200-1:500/p
pIHC: 1:200-1:500/p
pstrongReacts with/strongnbsp; :H | M | R/p
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h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
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