IQ-1

貨號 Cat. No.
1663-1
規格 Size
1 mg

Description

Alternate Name/Synonyms: 2-[(4-Acetylphenyl)azo]-2-(3,4-dihydro-3,3-dimethyl-1(2H)-isoquinolinylidene)-acetamide


Appearance: Orange solid


Formulation: N/A


CAS Number: 331001-62-8


Molecular Formula: C₂₁H₂₂N₄O₂


Molecular Weight: 362.42


Purity: ≥95% by HPLC


Solubility: DMSO


Storage Temp.: +4°C


Shipping Conditions: RT


Description: Maintains the undifferentiated state of embryonic stem cells. By targeting the PR72/130 subunit of the Ser/Thr phosphatase PP2A, it prevents β-catenin from switching coactivator usage from CBP to p300. The increase in β-cateinin/CBP mediated transcription at the expense of β-cateinin/p300-mediated transcription helps to maintain the murine stem cell pluripotency.


Handling: Protect from air and light

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