Ionomycin (free acid)

Alternate Name/Synonyms:

Appearance: Off-white to yellow solid

Formulation: N/A

CAS Number: 56092-81-01

Molecular Formula: C₄₁H₇₂O₉

Molecular Weight: 709.02

Purity: ≥97%

Solubility: DMSO

Storage Temp.: -20°C

Shipping Conditions: RT

Description: Antibiotic that acts as a potent and selective calcium ionophore; more effective than A23187.  Ionomycin binds Ca2+ in the 7.0-9.5 pH range with the resulting complex exhibiting intense UV absorption. Ionomycin induces apoptosis in immature B cell lines and in cultured embryonic rat cortical neurons.  More mature B cell lines do not undergo apoptosis, but are arrested in the G1 phase of the cell cycle.

Handling: Protect from light and moisture