Insulin Receptor-beta Antibody
Antibodies
- 貨號 Cat. No.
- 250724
- 規格 Size
- 0.1 mg
- 品牌 Brand
- Abbiotec
- Application 應用
- ELISA 、 IHC
- Reactivity
- Human 、 Mouse
Description
Insulin Receptor-beta (INSR) binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. Receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance.
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