INSR Antibody

h1 class=titleINSR Antibody/h1
div id=node-902 class=node ntype-antibodiesRabbit Polyclonal
div class=contentstyle type=text/css
!--
h4 {
margin: 30px 0 0 0;
padding: 0;
border-top: 1px solid #bbb;
background: #f8f8f8;
}
--/style
div class=product-table
table border=0 cellspacing=10 cellpadding=0 width=100%
tbody
tr
td valign=top width=50%
h4Catalog Number/h4
pstrong200110/strong/p
h4Unit/h4
pstrong0.1 mg/strong/p
h4Format/h4
pEach vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
pnbsp;/p
h4Data and Images/h4
/td
td valign=top
h4Description/h4
pINSR binds insulin and has a tyrosine protein kinase activity. The short isoform has a higher affinity for insulin. The receptor mediates the metabolic functions of insulin. The receptor binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). Defects in INSR are the cause of insulin resistance./p
br style=clear: both /
br style=clear: both /
h4Product Citations/h4
pnbsp;/p
h4Recommended Products/h4
pa href=http://abbiotec.com/peptides/insr-peptide350472 INSR Peptide/abr /
nbsp;/p
h4Alternate Names/h4
pInsulin receptor; CD220 antigen; IR; INSR/p
h4Accession No./h4
pa class=accession-link target=_blank href=http://www.expasy.org/uniprot/P06213P06213/abr /
a class=accession-link target=_blank href=http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=proteinamp;id=119395736NP_000199/abr /
nbsp;/p
h4Clonality/h4
pnbsp;/p
h4Antigen/h4
pnbsp;/p
pKLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human INSR./p
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pE: 1:500-1:1,000/p
pWB: 1:100-1:500/p
pstrongReacts with/strongnbsp; :H | M | R/p
pnbsp;/p
h4Storage/h4
pStore at -20deg;C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment./p
/td
/tr
/tbody
/table
/div
/div
/div