Influenza A [A/Guinea fowl/Hong Kong/WF10/99 (H9N2)] Hemagglutinin 1 (HA1) Protein, His Tag

Source : 

Influenza A [A/Guinea fowl/Hong Kong/WF10/99 (H9N2)] HA1, His Tag (HA2-V52H8) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Arg 338 (Accession # Q80KD9).

 

Molecule : Hemagglutinin 1 (HA1)

 

Synonyms : HA1,Hemagglutinin 1

 

Format : Powder

 

Category : Viral Proteins

 

Accession : Q80KD9

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 37.5 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.5 kDa. The protein migrates as 50-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

 

References :

(1) Suarez D.L.,et al., 1998, J. Virol. 72:6678-6688