IL-21 Polyclonal Antibody
- 貨號 Cat. No.
- 5551-100
- 規格 Size
- 100 ug
Description
pimg src=http://www.biovision.com/Merchant2/graphics/00000001/antibody-stock-miva.jpg alt= //p
pfont size=2 /font/p
pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide surrounding amino acid 124 of human IL-21 precursor/p
pbFORMULATION:/b 100 ug (0.5 mg/ml) peptide affinity purified rabbit anti-human IL-21 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbSPECIES REACTIVITY:/b human/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND DESCRIPTION:/b IL-21 is a novel cytokine that was recently identified in human and mouse. It has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel interleukin receptor) is a new member of the class I cytokine receptor family. IL-021R forms a complex with the common cytokine receptor ? chain and mediates IL-21 signaling. IL-21 and its receptor activates JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, HL-60, and THP-1 cell lines. IL-21 plays an important role in the proliferation and maturation of NK, B and T cell populations./p
pbAPPLICATION AND USAGE:/b The antibody can be used for Western blot analysis (1 ug/ml). However, the optimal conditions should be determined individually. Human HL-60 can be used as a positive control and an approximately 18 kDa band should be detected./p
pbFOR RESEARCH USE ONLY. Not to be used in humans. /b/p
pfont size=2 /font/p
pbHOST:/b Rabbit/p
pbIMMUNOGEN:/b Synthetic peptide surrounding amino acid 124 of human IL-21 precursor/p
pbFORMULATION:/b 100 ug (0.5 mg/ml) peptide affinity purified rabbit anti-human IL-21 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal./p
pbSPECIES REACTIVITY:/b human/p
pbSTORAGE CONDITIONS:/b Store at -20oC. For long term storage, aliquot and freeze at -70oC. Avoid repeated freeze/defrost cycles./p
pbBACKGROUND DESCRIPTION:/b IL-21 is a novel cytokine that was recently identified in human and mouse. It has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel interleukin receptor) is a new member of the class I cytokine receptor family. IL-021R forms a complex with the common cytokine receptor ? chain and mediates IL-21 signaling. IL-21 and its receptor activates JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, HL-60, and THP-1 cell lines. IL-21 plays an important role in the proliferation and maturation of NK, B and T cell populations./p
pbAPPLICATION AND USAGE:/b The antibody can be used for Western blot analysis (1 ug/ml). However, the optimal conditions should be determined individually. Human HL-60 can be used as a positive control and an approximately 18 kDa band should be detected./p
pbFOR RESEARCH USE ONLY. Not to be used in humans. /b/p