IL-2 Antibody

Catalog Number

251692

Unit

0.1 mg

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

Interleukin-2 (IL-2) is produced by T-cells in response to antigenic or mitogenic stimulation. IL-2 is required for T-cell proliferation and other activities crucial to regulation of the immune response. IL-2 also stimulates B-cells, monocytes, lymphokine-activated killer cells, NK cells and glioma cells. T-cell acute lymphoblastic leukemia (T-ALL) is caused by a chromosomal abberation in IL-2 gene. IL-2 (Proleukin, Chiron) is used as a treatment for patients with renal cell carcinoma and metastatic melanoma. This antibody recognizes and neutralizes human interleukin-2.

Alternate Names

Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2

Accession No.

P60568

 

Antigen

Recombinant human IL-2

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.