IL-17 Antibody

貨號 Cat. No.
5176-100
規格 Size
100 µg

Description

pstrongAntibody Target :/strongIl-17/p
pbHost: /bRabbit/p
pbAntibody Type: /bPolyclonal/p
pbIsotype: /bRabbit IgG/p
pbAntibody Form: /bAffinity Purified Antibody/p
pbImmunogen Sequence: /bE. coli expressed human IL-17/p
pbAccession#: /bAAC50341/p
pbGene ID: /b1155223/p
pbAppearance: /bColorless liquid/p
pbConcentration: /b0.5 mg/ml/p
pbFormulation: /b100 micro;g (0.5 mg/ml) affinity purified rabbit anti-human IL-17 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 10 mM EDTA, and 0.02% thymersal./p
pbPurification: /bAffinity purified/p
pbSpecies Reactivity: /bhu/p
pbApplication: /bWB/E/p
pbApplication amp; Usage: /bWestern blot analysis (0.5-1 micro;g/ml) and ELISA (2-4 micro;g/ml). However, the optimal conditions should be determined individually./p
pbStorage Temp.: /b-20 deg;C/p
pbShipping : /bgel pack/p
pbShelf Life: /b12 months/p
pbHandling: /bThe antibody solution should be gently mixed before use./p
pbBrief Background Descriptions: /bIL-17 was identified from a CD4+ T cells DNA library. IL-17 can be induced from primary peripheral blood CD4+ T cells upon stimulation. The cytokine exhibits a high degree of amino acid identity with HVS13, an open reading frame from a T lymphotropic Herpesvirus saimiri and with murine CTLA8. Supernatant from cells transfected with IL-17 induced IL-16 and IL-18 production and enhanced the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in human fibroblasts. IL-17 is a disulfide-linked homodimer of two 31.0 kDa subunits, each containing 136 amino acid residues./p

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